Frank Sönnichsen,  Dr. rer. nat.


  1. A. Sczostak, F. Sönnichsen, W. Tochtermann, E.-M. Peters, K. Peters, H.G. von Schnering, ‘The Photoisomerization of 3,6-Hexanooxepine-4,5-dicarboxylic Esters yields Tricyclo[,5]-undec-9-en-(3a,6-Methanooctahydroazulene)-Derivatives’, Tetrahedron Lett. 26, 5677-5680 (1985).
  2. W. Tochtermann, G. Olsson, A. Sczostak, F. Sönnichsen, H. Frauenrath, J. Runsink, E.-M. Peters, H.G. von Schnering, ‘Synthesis of Medium and Large Ring, XXIII. - Photochemical Rearrangements of 3,6-Alkanooxepine-4,5-dicarboxylic Esters’, Chem. Ber. 122, 199 - 207 (1989).
  3. W. Tochtermann, F. Sönnichsen, C. Wolff, E.-M. Peters, K. Peters, H.G. von Schnering, ‘Synthesis of Medium and Large Ring, XXV. - Synthesis of Functionalized trans-Hydrindanes with Angular a-Ketoester Group’, Chem. Ber. 122, 1969 - 1975 (1989).
  4. J.E. Van Eyk, F.D. Sönnichsen, R.S. Hodges, B.D. Sykes,  ‘Interaction of Actin 1-28 with Myosin and Troponin-I and the Importance of these Interactions to Muscle Regulation’ in Peptides as Probes in Muscle Research (ed. J.C. Rüegg), pp. 15-31, Springer Verlag Heidelberg (1991).
  5. F.D. Sönnichsen, J.E. Van Eyk, R.S. Hodges, B.D. Sykes, ‘Effect of Trifluoroethanol on Protein Secondary Structure: An NMR and CD Study using a Synthetic Actin Peptide’, Biochemistry 31, 8790-8798 (1992). (over 400 citations)
  6. B. Popp, N. Sdunnus, F. Sönnichsen, W. Tochtermann, E.-M. Peters, K. Peters, H.G. von Schnering, ‘Bridged and Branched Desoxy-methylfuranosides from 3,6-Hexanooxepines’, Tetrahedron Lett. 33, 8023-8026 (1992).
  7. F.D. Sönnichsen, H.L. Chao, P.L. Davies, B.D. Sykes, ‘The Nonhelical Structure of Type III Antifreeze Protein’, Science 259, 1154-1157 (1993).
  8. J.J. Wang, F.D. Sönnichsen, R. Boyko, R. S. Hodges, B.D. Sykes, ‘Evaluation of NMR Based Structure Determination of Flexible Peptides: Application to Desmopressin’, in Techniques in Protein Chemistry IV  (ed. R.H. Angeletti), pp. 569-575, Academic Press (1993).
  9. B. Popp, F. Sönnichsen, W. Tochtermann, ‘A New Stereoselective Approach to the Perhydroazulene Skeleton’, Tetrahedron: Assym. 4, 281-284 (1993).
  10. H.L. Chao, P.L. Davies, B.D. Sykes, F.D. Sönnichsen, ‘Use of Proline Mutants to help solve the NMR-Solution Structure of Type III Antifreeze Protein’, Protein Science 2, 1411-1428 (1993).
  11. C. McInnes, F.D. Sönnichsen, C.M. Kay, R.S. Hodges, B.D. Sykes, ‘NMR Solution Structure and Flexibility of a Peptide Antigen Representing the Receptor Binding Domain of Pseudomonas aeruginosa’, Biochemistry 32, 13432-13440 (1993).
  12. S.M. Ngai, F.D. Sönnichsen, R.S. Hodges, ‘Photochemical Crosslinking between Native Rabbit Skeletal Troponin C and Benzoylbenzoyl-TnI Inhibitory Peptide, Residues 104-115’, J. Biol. Chem 269, 2165-2172 (1994).
  13. W.A. Findlay, F.D. Sönnichsen, B.D. Sykes, ‘Solution Structure of the TR1C-Fragment of Skeletal Troponin C ‘, J. Biol. Chem. 269, 6773-6778 (1994).
  14. S.M. Ngai, F.D. Sönnichsen, R.S. Hodges, ‘Photochemical Crosslinking between Native Rabbit Skeletal Troponin C and Benzoylbenzoyl-TnI Inhibitory Peptide, Residues 104-115’, in "Peptides: Chemistry, Structure and Biology" (eds.  R.S. Hodges & J.A. Smith), 951-953, Escom, Leiden 1994.
  15. T.J. Sereda, C.T. Mant, F.D. Sönnichsen, R.S. Hodges,  ‘Reversed-phase chromatography of synthetic amphipathic a-helical peptides as a model for ligand-receptor interactions: Effect of changing hydrophobic environment on the relative hydrophilicity/hydrophobicity of amino acid side-chains.’ J. Chromat. A 676, 139-143 (1994).
  16. H.L. Chao, F.D. Sönnichsen, C. DeLuca, B.D. Sykes, P.L. Davies, ‘Structure-function-relationship of the globular Type III Antifreeze Protein: Identification of a cluster of hydrophilic residues required for binding to ice.’, Protein Science 3, 1760-1769 (1994).
  17. B. Tripet, N. Zhou, F.D. Sönnichsen, R.S. Hodges, ‘Hybritein: A de novo designed protein displaying cooperative interactions between a metal-ion binding loop and a helix-helix dimerization motif’, in "Peptides 1994" (Proceedings of the 23rd European Peptide Symposium), Elsevier 1995.
  18. F.D. Sönnichsen, B.D. Sykes, P.L. Davies, ‘Comparative modelling of the 3D-Structure of Type II antifreeze protein’, Protein Science 4, 460-471 (1995).
  19. J.R. Bagu, F.D. Sönnichsen, D. Williams, R.J. Andersen, B.D. Sykes , C.F.B. Holmes, ‘A comparison of the solution structures of microcystin-LR and motuporin’, Nature: Structural Biology 2, 114-116 (1995).
  20. P. Lavigne, L.H. Kondejewski, M.E. Houston Jr., F.D. Sönnichsen, B. Lix, B. D. Sykes, R.S. Hodges and C.M. Kay, ‘Preferential heterodimeric parallel coiled-coil formation by synthetic Max and c-Myc leucine zippers:  a description of putative electrostatic interactions responsible for the specificity of interaction’, J. Mol. Biol. 254 (3), 505-520  (1995). (over 70 citations)
  21. S. Rothemund, M. Beyermann, E. Krause, R.S. Hodges, B.D. Sykes, F.D. Sönnichsen, ‘Structure effects of double-D-amino acid replacements: An NMR- and CD-study using amphipathic model helices’, Biochemistry 34, 12954-12962 (1995).  (over 50 citations)
  22. B.D. Sykes, C.M. Slupsky, D.S. Wishart, F.D. Sönnichsen, S.M. Gagne, ‘NMR as a structural tool in complex biological systems: NMR studies of calcium sensitive interactions amongst muscle proteins’, in "NMR as a structural tool for macromolecules:  Current status and future directions" (Eds. B.D. Nageswara-Rao & M.D. Kemple), Plenum Press (1996).
  23. P. Lavigne, L.H. Kondejewski, M.E. Houston Jr., F.D. Sönnichsen, B. Lix, B. D. Sykes, R.S. Hodges and C.M. Kay, ‘Synthetic Max and C-Myc leucine zipper sequences preferentially form a disulfide bridged heterodimeric parallel coiled coil’, in "Peptides: Chemistry, Structure and Biology II" (eds.  R.S. Hodges & J.A. Smith), Escom, Leiden 1996.
  24. S. Rothemund, E. Krause, M. Beyermann, M. Dathe, M. Bienert, R. S. Hodges, B.D. Sykes, F.D. Sönnichsen, ‘Peptide destabilization by adjacent D-amino acids in single-stranded amphipathic a-helices’, Peptide Res. 9, 79-87 (1996).
  25. P. Lavigne, F.D. Sönnichsen, C.M. Kay, R.S. Hodges, ‘On the importance of the interhelical salt-bridges to coiled-coil stability and specificity of dimerization’, Science 271, 1136-1137, (1996). (over 50 citations)
  26. O.D. Monera, F.D. Sönnichsen, L. Hicks, C.M. Kay, R.S. Hodges, ‘The relative positions of alanine residues in the hydrophobic core control the formation of two-stranded or four stranded a-helical coiled coils.’ Protein Engineering 9(4), 353-363 (1996).
  27. S. Rothemund, E. Krause, M. Beyermann, M. Bienert, B.D. Sykes, F.D. Sönnichsen, ‘Assignment of the helical structure in neuropeptide Y: 1H-NMR spectroscopy and HPLC studies of methionine replacement analogs’, Biopolymers 39, 207-219 (1996).
  28. B. Lix, F.D. Sönnichsen, B. D. Sykes, ‘The role of transient changes in sample susceptibility in causing apparent multiple quantum Peaks in HOESY Spectra’, J. Magn. Res. A 121, 83-87 (1996).
  29. S. Rothemund, M. Bienert, M. Beyermann, E. Krause, B. Sykes, F.D. Sönnichsen, ‘Temperature dependence of amide proton NMR resonance frequencies: a monitor for intramolecular hydrogen bonds in helical peptides ?’, J. Biomol. NMR 8, 93-97 (1996).
  30. C.I. DeLuca, H. Chao, F.D. Sönnichsen, B.D. Sykes, P.L. Davies, ‘Effect of Type III antifreeze protein dilution and mutation on the growth inhibition of ice’, Biophys. J. 71, 2346-2355 (1996).
  31. F.D. Sönnichsen, C.I. DeLuca, P.L. Davies, B.D. Sykes, ‘Refined solution structure of Type III Antifreeze protein: hydrophobic groups may be involved in the energetics of the protein-ice interaction’, Structure 4 (15), 1325-1337 (1996). (over >60 citations)
  32. W. Gronwald, H. Chao, D.V. Reddy, B.D. Sykes, P.L. Davies, F.D. Sönnichsen, ‘NMR characterization of side-chain flexibility and backbone structure in Type I Antifreeze protein at near freezing temperatures’, Biochemistry 35, 16698-16704 (1996).
  33. J.D. Madura, M.S. Taylor, A. Wierzbicki, J.P. Harrington, C.S. Sikes, F.D. Sönnichsen, ‘The dynamics and binding of a Type III antifreeze protein in water and on ice’, J. Molec. Struc. (Theochem) 388, 65-77 (1996).
  34. J. G. Boothe, F.D. Sönnichsen, M.D. deBeus, A.M. Johnson-Flanagan,  ‘Purification, Characterization and Structural Analysis of a Plant Low-Temperature-Induced Protein, Plant. Phys. 113, 367-376 (1997).
  35. O. Vinogradova, P. Badola, L. Czerski, F.D. Sönnichsen & C.R. Sanders II, ‘E.coli Diaylglycerol Kinase: a case study in the application of solution NMR methods to an integral membrane protein’, Biophys. J. 72, 2688-2701 (1997).
  36. W. Gronwald, R.F. Boyko, F.D. Sönnichsen, D.S. Wishart, B.D. Sykes,  ‘ORB, a homology based program for the prediction of protein NMR chemical shifts’, J. Biomol. NMR 10, 165-179, (1997).
  37. S. Rothemund, Y.C. Liou, P.L. Davies, F.D. Sönnichsen, ‘Backbone structure and Dynamics of a hemolymph protein from Mealworm Beetle Tenebrio molitor’. Biochemistry 36, 13791- 13801 (1997).
  38. A. Wierzbicki, J.D. Madura, C. Salmon, F.D. Sönnichsen, ‘Modeling studies of binding of Sea Raven type II antifreeze protein to ice’, J. Chem. Info. Comp. Science 37, 1006-1010, (1997).
  39. H. Chao, P.L. Davies, R.S. Hodges, M. Houston, C.M. Kay, M.C. Loewen,  B.D. Sykes, F.D. Sönnichsen,  ‘A diminished role for hydrogen bonds in antifreeze protein binding to ice?’ Biochemistry 36, 14652 – 14660 (1997). (over 90 citations)
  40. D.V. Reddy, B. Shenoy, P. Carey, F.D. Sönnichsen, ‘Lack of observable biotin-protein interactions in the 1.3S subunit of transcarboxylase’, Biochemistry 36, 14676 – 14682 (1997).
  41. O. Vinogradova, F.D. Sönnichsen, C.R.Sanders II, ‘On choosing a detergent for solution NMR studies of membrane proteins, J. Biomol.NMR 4, 381-386 (1998).
  42. W. Gronwald, M.C. Loewen, B. Lix, A.J. Daugulis, F.D. Sönnichsen, P.L. Davies, B.D. Sykes, ‘The solution structure of Type II antifreeze protein reveals a new member of the lectin family. Biochemistry, 37, 4712-4721 (1998). (over 60 citations)
  43. M.E. Houston Jr., H. Chao, R.S. Hodges, B.D. Sykes, C.M. Kay, F.D. Sönnichsen, M.C. Loewen, P.L. Davies ‘Binding of an oligopeptide to a specific plane of ice’, J. Biol. Chem. 273, 11714-11718 (1998).
  44. O. Vinogradova, C. Carlin, F.D. Sönnichsen, C.R. Sanders II, ‘A membrane setting for the sorting motifs present in the adenovirus E3-13.7 protein which down-regulates the epidermal growth factor receptor’, J. Biol. Chem. 273, 17343-17350 (1998).
  45. F.D. Sönnichsen, P.L. Davies, B.D. Sykes, ‘NMR structural studies on antifreeze proteins’, Biochem. Cell Biol. 76, 284-293 (1998).
  46. W. Gronwald, R.F. Boyko, K. Rajarathnam, F.D. Sönnichsen, D.S. Wishart, B.D. Sykes,  ‘CAMRA: computer aided protein NMR assignment without sequential connectivities’, J. Biomol. NMR 12, 395-405 (1998).
  47. D.V. Reddy, S. Rothemund, B.C. Shenoy, P.R. Carey, F.D. Sönnichsen, ‘Structural Characterization of the entire 1.3S Subunit of Transcarboxylase from Propionibacterium Shermanii, Protein Science 7, 2156-2163 (1998).
  48. F.D. Sönnichsen, ’Antifreeze Proteins’, Biofutur 179, 52-53 (1998).
  49. M.C. Loewen, W. Gronwald, F.D. Sönnichsen, B.D. Sykes, P.L. Davies, ‘The ice-binding site of sea raven antifreeze protein is distinct from the carbohydrate-binding site of the homologous C-type lectin’. Biochemistry, 37, 17745-17753 (1998).
  50. C.L. Vance, C.M. Begg, S.J. Dubel, T.D. Copeland, F.D. Sönnichsen, M.W. McEnery, ‘N-type calcium channel/syntaxin/SNAP-25 complex probed by antibodies to II-III intracellular loop of the a1B subunit, Neuroscience, 90, 665-676 (1999).
  51. M.C. Loewen, H. Chao, M.E. Houston Jr., J. Baardsnes, R.S. Hodges, C.M. Kay, B.D. Sykes, F.D. Sönnichsen, P.L. Davies, ‘Alternative Roles for Asn and Leu in Type I antifreeze protein binding to ice.’ Biochemistry 38,4743-4749 (1999).
  52. G.C. Chu, T. Tomita, F. D. Sönnichsen, T. Yoshida, M. Ikeda-Saito, ‘The heme complex of HmuO, a bacterial heme degradation enzyme from Corynebacterium diphteriae, Structure of the catalytic site’, J. Biol. Chem 274, 24490-24496 (1999).
  53. S. Rothemund, Y.C. Liou, P.L. Davies, E. Krause, F.D. Sönnichsen,  ‘A new class of hexa-helical insect proteins as putative carriers of small hydrophobic ligands'. Structure- Folding and Design 7 (11), 1325-1332 (1999).
  54. D.V. Reddy, B.C. Shenoy, P.R. Carey, F.D. Sönnichsen, 'High resolution solution structure of 1.3S subunit of transcarboxylase from Propioni bacterium shermanii', Biochemistry 39, 2509-2516 (2000).
  55. P. Dalal, F.D. Sönnichsen, 'On the source of Type 1 Antifreeze Protein binding specificity to ice: A Monte-Carlo computational study. J. Chem. Inf. Comp. Sci. 40, 1276-1284 (2000).
  56. Y. Zhang, W. Swietnicki, M.G. Zagorski, W.K. Surewicz, F.D. Sönnichsen, 'Solution Structure of the prion protein variant associated with familial Creutzfeld Jakob disease', J Biol Chem 275, 33650-33654 (2000).
  57. P. Dalal, J. Knickelbein, A.D.J. Haymet, F.D. Sönnichsen, J.D. Madura . Hydrogen bond analysis of Type 1 antifreeze protein in water and the ice-/water interface.  Phys Chem Comm 7, 1-5 (2001).
  58. K. Oxenoid, F.D. Sönnichsen, C.R. Sanders . Conformationally Specific Misfolding of an Integral Membrane Protein.  Biochemistry 40, 5111-5118 (2001).
  59. Darin Brown, F.D. Sönnichsen, ‘Structure of Fish Antifreeze Proteins', in " Molecular Aspects of Fish and Marine Biology" (ed. Choy Hew), World Scientific Publishing Co. 109-138 (2002).
  60. R.E. Rivera-Hainaj, D.V. Reddy, K. Choowongkomon, F.D. Sönnichsen, P. R. Carey. 'Characterization of the carboxylate delivery module of transcarboxylase:  following the spontaneous decarboxylation of the 1.3S-CO2- subunit by NMR and FTIR spectroscopies', Biochemistry 41, 2191-2197 (2002.)
  61. P. D. Adams, Y. Chen, K Ma, M.G. Zagorski, F.D. Sönnichsen. M. McLaughlin, M.D. Barkley, ‘Intramolecular quenching of tryptophan fluorescence by the peptide bond in cyclic hexapeptides’, J. Am. Chem. Soc. 124, 9278-9286 (2002).
  62. K. Oxenoid, F.D. Sönnichsen, C.R. Sanders, ‚Topology and secondary structure of the N-terminal domain of diacylglycerolkinase, Biochemistry, 41, 12876-12882 (2002).
  63. M.S. Helfand, A.M. Hujer, F.D. Sönnichsen, R.A. Bonomo, ‘Unexpected advanced generation cephalosporinase activity of the Met69Phe mutant of SHV b-Lactamase’, J. Biol. Chem. 277, 47719-47723 (2002).
  64. Y. Huang, S. Dey, X. Zhang, F. Sönnichsen, P. Garner, ‘The a-helical Peptide Nucleic Acid Concept: Merger of Peptide Secondary Structure and Codified Nucleic Acid Recognition’, J. Am. Chem. Soc. 126, 4626-4640 (2004).
  65. K. Oxenoid, H. Kim, J. Jacob, F.D. Sönnichsen, C.R. Sanders, ‘NMR Resonance Assignments for a Helical 40 kDa Membrane Protein in a 96 kDa Micellar Complex’, J. Am. Chem. Soc. 126, 5048-5049 (2004).
  66. K. Choowongkomon, M.E. Hobert, C. He, C. Carlin, F.D. Sönnichsen, ‘Aqueous and Micelle-bound Structure of the Epidermal Growth Factor Receptor Juxtamembrane Domain Containing Basolateral Sorting Information, J. Biomol. Struc. Dyn. 21, 813-826 (2004).
  67. P. Carey, F.D. Sönnichsen and V.C. Yee, ‘Transcarboxylase: One of Nature’s Early Nanomachines’, IUBMB (Int Union Biochem Molec Biol ) Life, 56 (10), 575-583 (2004).
  68. C. Tian, M.D. Karra, C.D. Ellis, J. Jaicob, K. Oxenoid, F.D. Sönnichsen, C.R.Sanders, ‘Membrane Protein Preparation for TROSY NMR screening’, Meth. Enzymology (ed. T.L. James), Vol 394, Part C, 321-335 (2005).
  69. K. Choowongkomon, C.R. Carlin, F.D. Sönnichsen, ‘A Structural Model for the Membrane-Bound Form of the Juxtamembrane Domain of the Epidermal Growth Factor Receptor’. J. Biol. Chem. 280, 24043-24052 (2005). 
  70. A. Tsacoumango, S. J. Kil, L. Ma, F. D. Sönnichsen, C. Carlin. ‘Role for EGF receptor residues 679-LL during post-endocytic sorting to lysosomes independent of receptor ubiquitination’. J. Cell Science 118, 3959-3971 (2005).
  71. C.R. Sanders, F.D. Sönnichsen, Solution NMR of Membrane Proteins: Practice and Challenges, Magn. Reson. Chem. 44, S24-40 (2006).
  72. R.C. Page, J. D. Moore, H. Nguyen, M. Sharma, R. Chase, F.P. Gao, T.A. Cross, C.K. Mobley, C.R. Sanders, L. Ma, F.D. Sönnichsen, S. Lee, and S.J. Opella, ‘Comprehensive evaluation of solution nuclear magnetic resonance spectroscopy sample preparation for helical integral membrane proteins’,  Journal of Structural and Functional Genomics 1, 51-64 (2006).
  73. N. Holland, Y. Nishimiya, S. Tsuda, F.D. Sönnichsen, ‘Activity of a Two-Domain Antifreeze Protein is Not Dependent on Linker Sequence’, Biophysical J. 92, 541-546 (2007).
  74. A.H. Shah, N.L. Cianciola, J.L. Mills, F.D. Sönnichsen, C. Carlin, ‘Adenovirus RIDa Regulates Endosome Maturation by Mimicking GTP-Rab7’, Journal Cell Biology 179, 965-980 (2007).
    Faculty1000 review:
  75. N.J. Cobb, FD Sönnichsen, H. Mchaourab, W.K. Surewicz, ‘Molecular architecture of human prion protein amyloid, Proc. Nat. Acad Sci., 104, 18946-18951 (2007).
  76. M.J. Hake, K.Choowongkomon, O. Kostenko, C.R. Carlin, F.D. Sönnichsen, ‘Specificity Determinants of a Novel NCK Interaction with the Juxtamembrane Domain of the Epidermal Growth Factor Receptor’, Biochemistry 47, 3096-3108 (2008).
  77. M.H. Chang, J. DiPiero, F.D. Sönnichsen, M.F. Romero, ‘Entry to “HCO3- tunnel” revealed by human mutation and structural model’, J Biol Chem 283, 18402-18410 (2008).
  78. N. Holland, S. Tsuda, F D. Sönnichsen, ‘Two domains of RD3 antifreeze protein Diffuse Independently’, Biochemistry 47, 5935-5941 (2008).
  79. H.A. Shaikh, F.D. Sönnichsen, T.K.Lindhorst, Carbohydr. Res. 343,1665-1674 (2008).
  80. C. Kang, C. Tian, F.D. Sönnichsen, J.A. Smith, J. Meiler, A.L. George, G.G. Vanoye, H.J. Kim, C.R. Sanders, ‘Structural Basis for Modulation of a Voltage-Gated Potassium Channel by a KCNE Accessory Subunit’, Biochemistry, 47,7999-8006 (2008).
  81. F. Westphal, P. Rösner, F.D. Sönnichsen, Mass and NMR Spectroscopic Characterization of 3,4 Methylenedioxypyrovalerone: a Designer Drug with a-Pyrrolidinophenone Structure, Forensic Sci Int, 190, 1-8 (2009).
  82. R. Siewertsen, F. Renth, F. Temps, F. Sönnichsen, ‚Parallel Ultrafast E-C Ring Closure and E-Z Isomerization in a Photochromic Furylfulgide Studied by Femtosecond Time-Resolved Spectroscopy, Phys Chem Chem Phys 11, 5952 - 5961 (2009).
  83. W.D. Van Horn, H-K Kim, C.D. Ellis, A. Hadziselimovic, E.S. Sulistijo, M.D. Karra, C Tian, F.D. Sönnichsen, CR Sanders, Solution NMR Structure of the Membrane-integral DAGK Kinase, Science 324, 1726-1729 (2009).
  84. J.E. Eckelmann, V. Saggiomo, F.D. Sönnichsen, U. Lüning, ‘The first supramolecular triplet complex, New J. Chem 34,1247-1250 (2010).
  85. A. Mohebbi, E. Mucke, G. Schaller, F. Koehler, F.D. Sönnichsen, L. Ernst, C. Näther, R. Herges, ‘Single and Double Twisted [36]Annulenes, Synthesis and Calculations’, Chem. Europ J. 7767-7772 (2010).
  86. S. Thies, C. Bornholdt, F. Köhler, F.D. Sönnichsen, C. Näther, R. Herges, F. Tuczek, ‘Coordination-Induced Spin Crossover (CISCO) through Axial Bonding of Substituted Pyridines to Nickel-Porphyrins: s-Donor vs p-Acceptor Effects, Chem.Europ. J. 10074-10083 (2010).
  87. F. Westphal, Th. Junge, F. Sönnichsen, P. Rösner, J. Schäper, Ein neuer Wirkstoff in SPICE-artigen Kräutermischungen: Charakterisierung von JWH-250, seinen Methyl- und Trimethylsilylderivaten, Toxichem Krimtech 77 (1) 46-58 (2010).
  88. B. Harbaum-Piayda, K. Oehlke, F.D. Sönnichsen, P. Zacchi, R. Eggers, K. Schwarz,  ‘New Phenolic Compounds in Rapeseed Oil’, Food Chemistry 123, 607-615 (2010).
  89. K. Oehlke, A. Heins, H. Stöckmann, F.D. Sönnichsen, K. Schwarz, ‘New Insights into the antioxidant activity of Trolox in o/w emulsions. Food Chemistry 124, 781-787 (2011).
  90. S. Venkataramani, U. Jana, M. Dommaschk, F.D. Sönnichsen, F. Tuczek, R. Herges, Magnetic Bistability of Molecules in Homogeneous Solutions at Room Temperature’, Science 331, 445-448 (2011).
  91. F. Strübe, R. Siewertsen, F.D. Sönnichsen, F. Renth, F. Temps, J. Mattay, Photochromism of Furyl Fulgides Influenced by Sterical Modification of the Furyl Backbone, Chem. Eur. J. 10,1947-1955 (2011).
  92. M.K. Parr; G.Opfermann, H.M. Geyer, F Westphal, F.D Sönnichsen, J. Zapp, D. Kwiatkowska, W. Schänzer, ‘Seized Designer Supplement named "1-Androsterone": Identification as 3β-Hydroxy-5α-androst-1-en-17-one and its Urinary Elimination’, Steroids 76, 540-547 (2011).
  93. K. Schwekendiek, H. Kobarg, L. Daumlechner, F.D. Sönnichsen and T.K. Lindhorst, Photodimerisation of glycothymidines in solution and in micelles, Chem. Commun. 47, 9399-9401 (2011).
  94. F. Westphal, F.D. Sönnichsen, S. Thiemt, ‘Identification of 1-butyl-3-(1-(4-methyl)naphthoyl)indole in a herbal mixture’, Forensic Sci. Int. 215, 8-13 (2012). ePub May2011.
  95. H. Sell, A. Gehl, F.D. Sönnichsen, R. Herges, ‘Thermodynamic and kinetic stabilization of divanadate in the monovanadate/divanadate equilibrium using a Zn-cyclene derivative: Towards a simple ATP synthase model’, Beilstein J. Org. Chem. 8, 81-89 (2012).
  96. A. Bannwarth, S.O. Schmidt, G. Peters, F.D. Sönnichsen, W. Thimm, Rainer Herges, and Felix Tuczek, ‘Fe(III) Spincrossover Complexes with Photo¬isomerizable Ligands: Experimental and Theoretical Studies on the LD-LISC Effect, Eur. J . Inorg Chem. (2012).
  97. S. Jung, F. D. Sönnichsen, C. Hung, C. Boidin-Wichlacz, C. Gelhaus, M. Leippe, A. Tasiemski, R. Podschun, A. Tholey, J. Grötzinger, ’Macin Family of Antimicrobial Proteins combines antimicrobial and nerve repair activities’, J Biol Chem. 287, 14246-14258 (2012).
  98. B. Spudy, F.D. Sönnichsen, G.H. Waetzig, J. Grötzinger, S. Jung, , ‘Identification of the structural traits mediating the antimicrobial activity of a chimeric peptide of human β-defensins 2 and 3,’ BBRC 427, 207-211 (2012).
  99. M. Michalek, F.D. Sönnichsen, R. Wechselberger, A.J. Dingley, Chien-Wen Hung, A. Kopp, H. Wienk, Maren Simanski, R. Herbst, I. Lorenzen, F. Marciano-Cabral, C. Gelhaus, T. Gutsmann, A. Tholey, J. Grötzinger, M. Leippe, New toxin from the soil: Structure and function of a unique pore-forming protein from a free-living amoeba and human pathogen, Nature Chem Biol. 9 , 37-42 (2013).
  100. J. Bahrenburg, C.M. Sievers, J.B. Schönborn, B. Hartke, F. Renth, F. Temps, C. Näther, F.D. Sönnichsen, ‘Photochemical properties of multi-azobenzene compounds’ , Photochem. Photobiol Sci 12, 511-518 (2013).
  101. P. J. Barrett, J. Chen, M.K. Cho, J.H Kim, Z. Lu, S. Mathew, D. Peng, Y. Song, W.ED. Van Horn, T. Shuang, F.D. Sönnichsen, C.R. Sanders, “The Quiet Renaissance of Protein Nuclear Magnetic Resonance’, Biochemistry 52, 1303-1320 (2013).
  102. S. Düsterhöft, S. Jung, CW Hung, A Tholey, F.D. Sönnichsen, J. Grötzinger, , I. Lorenzen ‘The membrane-proximal domain of ADAM17 represents the putative molecular switch of its activity operated by Protein-disulfide isomerase. J. Amer. Chem. Soc 135, 5776–5781 (2013).
  103. C. Gradert, J. Krahmer, F.D. Sönnichsen, C. Näther, F. Tuczek‚ ‘Small-Molecule Activation with Molybdenum(0) Complexes Supported by Mixed Imidazol-2-Ylidene/Phosphanyl Hybrid Ligands – Electronic and Structural Consequences of Substituting a Phosphane by a Carbene Group‘, Europ. J. Inorganic Chem. in press (2013).
  104. K. Röttger, F.D. Sönnichsen, F. Temps, ‘Ultrafast Electronic Deactivation Dynamics of the Inosine Dimer – A Model Case for H-Bonded Purine Bases’, Photochem. Photobiol. Sci 12, 1466-1473 (2013).
  105. Q. Kong, J. L. Mills, B. Kundu, X. Li, L. Qing, K. Surewicz, I. Cali, S. Huang, M. Zheng, W. Swietnicki, F.D. Sönnichsen, P. Gambetti, W.K. Surewicz, ‘Thermodynamic Stabilization of the Folded Domain of Prion Protein Inhibits Prion Infection in Vivo’, Cell Reports, 4(2), 284-254 (2013).S. Rothemund, F.D. Sönnichsen, T. Polte ‘Therapeutic potential of the peptide leucine arginine (pLR) as a new non-plant bowman-birk like serine-protease inhibitor PLR’, J. Med. Chem. 56, 6732-6744 (2013).
  106. R. Golowin, A. Holzheid, F.D. Sönnichsen, N.V. Chukanov, Formation of solid bituminous matter in pegmatites: constraints from experimentally formed organic matter on microporous silicate minerals, Chemie der Erde 74,343-351(2014).
  107. M. Schmidt, H. Sun, H. Abromeit, G. Scriba, F.D. Sönnichsen, S. Becker, M. John, U.M. Reinscheid, ‚ Hidden flexibility of Strychnine, ‘ Annal. Chemie (2014)
  108. J.K. Keppler, F.D. Sönnichsen, P.C. Lorenzen, K. Schwarz, ‘Differences in heat stability and ligand binding among β-lactoglobulin genetic variants A, B and C’, Biochim. Biophys. Acta 1844, 1083-1093 (2014).
  109. Aurélie Tasiemski, Sascha Jung, Céline Boidin-Wichlacz, Didier Jollivet, Virginie Cuvillier-Hot, Florence Pradillon, Costantino Vetriani, Oliver Hecht, Frank D Sönnichsen, Christoph Gelhaus, Chien-Wen Hung, Andreas Tholey, Matthias Leippe, Joachim Grötzinger, Françoise Gaill, ‘Characterization and Function of the First Antibiotic Isolated from a Vent Organism: The Extremophile Metazoan Alvinella pompejana.’, PLoS ONE 9, e95737 (2014), DOI:10.1371/journal.pone.0095737 .
  110. C. Gradert, J. Krahmer, F.D. Sönnichsen, c. Näther, F. Tuczek, ‘Molybdenum (0)-carbonyl complexes supported by mixed benzimidazol-2-ylidene/phosphine ligands: Influence of benzannulation on the donor properties of the NHC groups’, J. Organometallic Chemistry 770, 61-68 (2014).
  111. V. Chandrasekaran, E. Johannes, H. Kobarg, F.D. Sönnichsen, T.K. Lindhorst, ‚Synthesis and photochromic properties of configurationally varied azobenzene glycosides‘ Chem. Open 3, 99-108, 2014. (Cover illustration).
  112. M. Dommaschk, C. Schütt, S. Venkataramani, U. Jana, C. Näther, F.D. Sönnichsen, R. Herges, ‚Rational design of a room temperature molecular spin switch: the light-driven coordination induced spint state switch (LD-CISSS) approach‘, Dalton Trans 43, 17395-17405 (2014).
  113. F. Westphal, F.D. Sönnichsen, S. Knecht, V. Auwärter, L. Huppertz, ‚‘Two thiasolylindoles and a benzimidazole: Novel compounds on the designer drug market with potential cannabinoid receptor activity‘, Forensic Science International 249, 133-147 (2015).
  114. M. Michalek, S. Jung, M.R. Shomali, S. Cauchard, F.D. Sönnichsen, J. Grötzinger ‚‘Solution structure and functional studies of the highly potent equine antimicrobial peptide DEFA1‘, Biochem Biophys Res Comm 459, 668-672 (2015).
  115. A. Müller, H. Kobarg, V. Chandrasekaran, J.Gronow, F.D. Sönnichsen, T.K. Lindhorst, ‚Synthesis of bifunctional glycoconjugates for Cysteine-based photosensitive Cross-linking with bioactive peptides, Chemistry 21, 13723-13731 (2015).
  116. J. Strüben, M. Lipfert, J.O. Springer, C.A. Gould, P.J. Gates, F.D. Sönnichsen, A.Staubitz ‚High-yield lithiatioation of azobenzenes by tin-lithium exchange‘, Chemistry 27, 11165-11173 (2015).
  117. M. Dommaschk, M. Peters, f. Gutzeit, C. Schütt, C. Näther, F.D. Sönnichsen, S. Tiwari, C. Riedel, S. Boretius, R. Herges, ‚Photoswitchable magnetic resonance imaging contrast by improved light-driven coordination-induced spin state switch, J. Amer. Chem. Soc 137, 7552-7555 (2015).
  118. H. Krudopp, F.D. Sönnichsen, A. Steffen-Heins, ‚Partitioning of nitroxides in dispersed systems investigated by ultrafiltration, EPR and NMR spectroscopy‘, J. Colloid Interfac Sci 452, 15-23 (2015).
  119. S. Jung, J. Fischer, B. Spudy, T. Kerkow, F.D. Sönnichsen, L. Xue, A.M. Bonvin , P. Goettig, V. Magdolen, U. Meyer-Hoffert, J. Grötzinger , 'The solution structure of the kallikreinin-related peptidases inhibitor SPINK6', Biochem. Biophys. Res. Commun. 47, 103-108 (2016).
  120. Chen X, Schreiber K, Appel J, Makowka A, Fähnrich B, Roettger M, Hajirezaei MR, Sönnichsen FD, Schönheit P, Martin WF, Gutekunst K., ‘The Entner-Doudoroff pathway is an overlooked glycolytic route in cyanobacteria and plants.’, Proc Natl Acad Sci U S A. 113, 5441-5446 (2016).
  121. Sommer A, Kordowski F, Büch J, Maretzky T, Evers A, Andrä J, Düsterhöft S, Michalek M, Lorenzen I, Somasundaram P, Tholey A, Sönnichsen FD, Kunzelmann K, Heinbockel L, Nehls C, Gutsmann T, Grötzinger J, Bhakdi S, Reiss K., ‘Phosphatidylserine exposure is required for ADAM17 sheddase function.’, Nat Commun. 7, 11523 (2016).
  122. Thiedemann B, Gliese PJ, Hoffmann J, Lawrence PG, Sönnichsen FD, Staubitz A., ‘High molecular weight poly(N-methyl-B-vinylazaborine) - a semi-inorganic B-N polystyrene analogue.’, Chem Commun (Camb). 53, 7258-7261 (2017).
  123. Guan C, Parrot D, Wiese J, Sönnichsen FD, Saha M, Tasdemir D, Weinberger F, ‘Identification of rosmarinic acid and sulfated flavonoids as inhibitors of microfouling on the surface of eelgrass Zostera marina.’, Biofouling. 2017, 1-14. doi: 10.1080/08927014.2017.1383399. [Epub ahead of print]

last update October 2017